Educational

Resources

Explore ActiGraph's educational resources to gain a deeper understanding of Digital Health Technologies in clinical trials.

Resources

The Importance of Patient-focused Drug Development

Clinical benefit is a positive effect on how the patient feels, functions, and survives. For study teams to demonstrate clinically meaningful effect(s) of a therapeutic intervention, it's critical to understand how a patient is impacted by a condition to define relevant concepts of interest and select appropriate measures for clinical trial endpoints.

Therapeutic Area Indication Most Significant Symptoms Reported by Patients Meaningful Aspects of Health Candidate Digital Measures Digital Measures Report
Neurology Parkinson's Disease
  • Motor Symptoms
  • Cognitive Dysfunction
  • Sleep Disturbances
  • Cardinal Symptoms
  • Sleep 
  • Bradykinesia Score
  • Dyskinesia Score
  • Percent Time Tremor
  • Wake after sleep onset
View Report
Cardiology Hypertrophic Cardiomyopathy (HCM)
  • Shortness of Breath or Trouble Breathing
  • Exercise Intolerance
  • Lightheadedness, Dizziness, Fainting
  • Arrhythmias / Heart Palpitations
  • Physical Activity
  • Gait and Mobility
  • Vital Signs
  • Non-sedentary time 
  • Walking bouts 
  • Walking speed
  • Arrhythmia burden
View Report
Dermatology Atopic Dermatitis (Eczema)
  • Itchiness
  • Red, Inflamed Skin
  • Pain
  • Sleep Disturbances
  • Scratch 
  • Sleep
  • Wake after sleep onset
  • Total scratch time
View Report
Respirology Idiopathic Pulmonary Fibrosis (IPF)
  • Coughing
  • Shortness of Breath
  • Fatigue
  • Physical Activity
  • Cough
  • Moderate-to-vigorous physical activity
  • Non-sedentary time
  • Step count
  • Cough
View Report
Respirology Obstructive Sleep Apnea (OSA)
  • Fatigue and Daytime Sleepiness
  • Unrefreshing Sleep
  • Cognitive Issues
  • Physical Activity
  • Sleep 
  • Vital Signs
  • Non-sedentary time 
  • Wake after sleep onset
  • Night time oxygen saturation
View Report
Cardiology Pulmonary Arterial Hypertension (PAH)
  • Shortness of Breath
  • Fatigue
  • Physical Activity
  • Gait and Mobility
  • Moderate-to-vigorous physical activity
  • Non-sedentary time
  • Walking bouts 
  • Walking speed
View Report
Dermatology Psoriasis
  • Itching
  • Flaking or Scaling Skin
  • Dry, Cracked Skin that may bleed
  • Stinging, Burning, and/or Pain
  • Scratch 
  • Sleep
  • Physical Activity
  • Wake after sleep onset
  • Total scratch time
  • Step count
  • Non-sedentary time
View Report
Neurology Narcolepsy
  • Excessive Daytime Sleepiness
  • Cataplexy
  • Sleep Dysfunction
  • Cognitive Effects and Automatic Behaviors
  • Physical Activity
  • Sleep
  • Vital Signs
  • Non-sedentary time 
  • Wake after sleep onset
  • Daytime immobility bouts
View Report
Respirology Asthma
  • Shortness of Breath or Trouble Breathing
  • Frequent Coughing
  • Chest Tightness
  • Mood changes
  • Physical Activity
  • Sleep
  • Cough
  • Moderate-to-vigorous physical activity
  • Non-sedentary time
  • Step count
  • Wake after sleep onset
  • Cough
View Report
Rheumatology Osteoarthritis (OA)
  • Pain and Tenderness
  • Stiffness
  • Functional Limitations and Impaired Mobility
  • Fatigue and Sleep Disturbances
  • Physical Activity
  • Sleep
  • Gait and Mobility
  • Moderate-to-vigorous physical activity
  • Non-sedentary time
  • Step count
  • Walking bouts
  • Walking speed
  • Wake after sleep onset
View Report
Oncology Cancer Cachexia
  • Muscle Weakness
  • Fatigue/Feelings of Tiredness
  • Loss of Appetite
  • Severe Weight Loss
  • Physical Activity
  • Gait and Mobility
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Walking bouts 
  • Walking speed
View Report
Neurology Myotonic Dystrophy (DM)
  • Muscle Weakness and Myotonia
  • Fatigue
  • Pain
  • Heart Problems
  • Physical Activity
  • Gait and Mobility
  • Sleep
  • Vital Signs
  • Non-Sedentary Time
  • Step Count
  • Walking Bouts
  • Walking Speed / Cadence
  • Wrist 6 Minute Peak Activity
  • Specific Wrist Movement Metrics
  • Wake After Sleep Onset
  • Arrhythmia Burden
View Report
Neurology Spinal Muscular Atrophy (SMA)
  • Fatigue
  • Muscle Weakness and Loss of Mobility
  • Breathing Difficulties
  • Physical Activity
  • Gait and Mobility
  • Non-Sedentary Time
  • Step Count
  • Walking Bouts 
  • Walking Speed
  • Wrist 6 Minute Peak Activity 
  • Specific Wrist Movement Metrics
View Report
Neurology Kennedy’s Disease (KD) / Spinal and bulbar muscular atrophy (SBMA)
  • Muscle Weakness and Cramping
  • Fatigue
  • Breathing Difficulties
  • Balance Issues
  • Physical Activity
  • Gait and Mobility 
  • Non-Sedentary Time
  • Walking Bouts 
  • Walking Speed / Cadence
View Report
Neurology Amyotrophic Lateral Sclerosis (ALS)
  • Muscle Weakness and Fatigue
  • Shortness of Breath
  • Difficulty Sleeping
  • Speech Problems
  • Physical Activity
  • Gait and Mobility 
  • Sleep 
  • Speech
  • 6 Minute Peak Activity
  • Walking Bouts 
  • Walking Speed / Cadence
  • Step Counts
  • Specific Wrist Movement Metrics
View Report
Neurology Huntington's Disease
  • Cognitive Impairment
  • Chorea and other Motor Symptoms
  • Depression or Anxiety
  • Physical Activity
  • Gait and Mobility
  • Chorea
  • Sleep
  • Total Activity Counts
  • Walking Bouts
  • Walking Speed / Cadence
  • Step Counts
  • Wrist Activity Counts
  • Dyskinesia Score
View Report
Metabolic and Endocrinology Nonalcoholic Steatohepatitis (NASH)
  • Fatigue / Low Energy
  • Abdominal Pain
  • Physical Activity
  • Gait and Mobility
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Walking bouts 

Coming Soon

Neurology Sarcopenia
  • Muscle Loss, Muscle Weakness, Frailty
  • Balance Problems and Falling
  • Fatigue
  • Muscle Pain
  • Physical Activity
  • Gait and Mobility
  • Sleep 
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Walking bouts 
  • Walking speed

Coming Soon

Rheumatology Systemic Sclerosis
  • Painful cold sensitivity
  • Gastrointestinal symptoms
  • Chronic Fatigue
  • Contractures and Calcinosis of Digits
  • Physical Activity
  • Sleep 
  • Non-sedentary time 
  • Wake after sleep onset

Coming Soon

Rheumatology Inclusion Body Myositis (IBM)
  • Muscle Weakness and Atrophy
  • Dysphagia
  • Fatigue
  • Physical Activity
  • Sleep
  • Gait and Mobility
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Step count
  • Walking speed
  • Wake after sleep onset

Coming Soon

White Papers and eBooks

Explore how ActiGraph's Digital Health Technologies are reshaping healthcare. Discover the valuable insights of ActiGraph's subject matter experts through our collection of White Papers and eBooks, and revolutionize the ability to remotely obtain and analyze real-world data.

White Paper

Here, we’ve collected 4 real-world examples of clinical trials that incorporated DHTs. We assess the aspect of clinic...

White Paper

Sensor-based digital health technologies (DHTs) have revolutionized the ability to remotely obtain and analyze clinic...

White Paper

In December 2021, the FDA released its first guidance specific to the use of digital health technologies (DHTs).

eBook

Neurological diseases are inherently complex, and drug development in neurology is notoriously challenging.

White Paper

Scratching an itch can result in further problems such as inflammation and lesions that, in turn...

White Paper

Usability is critical to wearable-enabled clinical trials, which is why the FDA calls usability...

White Paper

In this ActiGraph white paper, we cover the operational challenges of DCTs and how actigraphy is being used to clear ...


Recent On-Demand Webinars

Watch previously recorded webinar discussions with industry leaders, who share their expertise in digital health technologies.

November 1, 2023

Watch this exclusive webinar as we unveil the ActiGraph LEAP™, our latest innovation in wearable digital health techn...

August 29, 2023

This 1-hour webinar explores how sensor-based digital health technologies (DHTs) can be used to collect clinically me...

April 1, 2023

More than 90% of rare diseases do not have any treatment, representing a substantial unmet need for patients.

January 18, 2023

Digital transformation in healthcare and clinical research has been slower to progress than in other economic sectors...

Recent Webinars
Watch previously recorded webinar discussions with industry leaders, who share their expertise in digital health technologies.
LEAP into the Future of Patient-Centered Research: Introducing the Latest Innovation in Wearable Technology
Advancing Heart Failure Research with Digital Measures
Accelerating Rare Disease Drug Development with Wearable Digital Health Technologies

ActiGraph News

Checkout the latest press releases, updates and videos.

PENSACOLA, FL, October 30, 2024 -ActiGraph, a leading provider of wearable technology and scientific services for clinic...
PENSACOLA, FL, June 12, 2024 – ActiGraph, the leading provider of wearable digital health technology (DHT) solutions for...
PENSACOLA, FL, February 20, 2024 – ActiGraph and Cambridge Cognition, leading providers of wearable digital health techn...
PENSACOLA, FL, February 9, 2024 – ActiGraph, a leading provider of wearable technology and scientific services for acade...
PENSACOLA, FL, November 20, 2023 - ActiGraph, a leader in wearable digital health technology and digital health sciences...

ActiGraph Blog

Check out the latest industry focused articles.

As we embark on another exciting year for the digital health landscape, I wanted to take a moment to reflect on the stri...
New weight management medications, such as GLP-1 receptor agonists, have dramatically altered the landscape of obesity t...
Sleep is a complex and multifaceted physiological process. In humans, not only is sleep required for survival, but a gro...
Last month ActiGraph released a new version of our academic software platform, ActiLife 7. Our legacy ActiLife data proc...
Digital health technologies (DHT) can collect objective, multi-dimensional data passively and remotely with a limited bu...
Wearable, sensor-based digital health technologies (DHTs) can help biotech and pharma teams accelerate their clinical de...

Upcoming Events

Engage with the ActiGraph team at one of our scheduled virtual presentations or in-person conferences.

Clinical Trial Innovation Summit 2024
CONFERENCE
Clinical Trial Innovation Summit
October 22, 2024
October 22, 2024
San Francisco, CA
ActiGraph representatives will be attending this event. Please contact meetings@theactigraph.com to schedule a meeting.
Obesity Week 2024
CONFERENCE
Obesity Week
November 3, 2024
November 3-6, 2024
San Antonio, TX
ActiGraph representatives will be attending this event. Please contact meetings@theactigraph.com to schedule a meeting.
CONFERENCE
Huntington's Study Group
November 7
 - 
9, 2024
November 7-9, 2024
Cincinnati, OH
ActiGraph representatives will be attending this event. Please contact meetings@theactigraph.com to schedule a meeting.
CONFERENCE
Medidata NEXT
November 13
 - 
14, 2024
November 13-14, 2024
New York, NY
ActiGraph representatives will be attending this event. Please contact meetings@theactigraph.com to schedule a meeting.
CONFERENCE
7th Annual Digital Implementation Summit
November 13, 2024
November 13, 2024
Cambridge, MA
ActiGraph representatives will be attending this event. Please contact meetings@theactigraph.com to schedule a meeting.
CONFERENCE
Parkinson Study Group
December 5
 - 
8, 2024
December 5, 2024
Nashville, TN
ActiGraph representatives will be attending this event. Please contact meetings@theactigraph.com to schedule a meeting.
CONFERENCE
SCOPE
February 3
 - 
6, 2025
February 3-6, 2025
Orlando, FL
ActiGraph representatives will be attending this event. Please contact meetings@theactigraph.com to schedule a meeting.
CONFERENCE
ADDS 2025
February 10
 - 
12, 2025
February 10-12, 2025
Pensacola Beach, FL
ActiGraph representatives will be attending this event. Please contact meetings@theactigraph.com to schedule a meeting.

ActiGraph

Pioneering the Digital Transformation of Clinical Research