📣 ADDS Basel 2025  |  September 12, 2025 in Basel, Switzerland

Educational

Resources

Explore ActiGraph's educational resources to gain a deeper understanding of Digital Health Technologies in clinical trials.

Resources

The Importance of Patient-focused Drug Development

Clinical benefit is a positive effect on how the patient feels, functions, and survives. For study teams to demonstrate clinically meaningful effect(s) of a therapeutic intervention, it's critical to understand how a patient is impacted by a condition to define relevant concepts of interest and select appropriate measures for clinical trial endpoints.

Therapeutic Area Indication Most Significant Symptoms Reported by Patients Meaningful Aspects of Health Candidate Digital Measures Digital Measures Report
Neurology Parkinson's Disease
  • Motor Symptoms
  • Cognitive Dysfunction
  • Sleep Disturbances
  • Cardinal Symptoms
  • Sleep 
  • Bradykinesia Score
  • Dyskinesia Score
  • Percent Time Tremor
  • Wake after sleep onset
View Report
Cardiology Hypertrophic Cardiomyopathy (HCM)
  • Shortness of Breath or Trouble Breathing
  • Exercise Intolerance
  • Lightheadedness, Dizziness, Fainting
  • Arrhythmias / Heart Palpitations
  • Physical Activity
  • Gait and Mobility
  • Vital Signs
  • Non-sedentary time 
  • Walking bouts 
  • Walking speed
  • Arrhythmia burden
View Report
Dermatology Atopic Dermatitis (Eczema)
  • Itchiness
  • Red, Inflamed Skin
  • Pain
  • Sleep Disturbances
  • Scratch 
  • Sleep
  • Wake after sleep onset
  • Total scratch time
View Report
Respirology Idiopathic Pulmonary Fibrosis (IPF)
  • Coughing
  • Shortness of Breath
  • Fatigue
  • Physical Activity
  • Cough
  • Moderate-to-vigorous physical activity
  • Non-sedentary time
  • Step count
  • Cough
View Report
Respirology Obstructive Sleep Apnea (OSA)
  • Fatigue and Daytime Sleepiness
  • Unrefreshing Sleep
  • Cognitive Issues
  • Physical Activity
  • Sleep 
  • Vital Signs
  • Non-sedentary time 
  • Wake after sleep onset
  • Night time oxygen saturation
View Report
Cardiology Pulmonary Arterial Hypertension (PAH)
  • Shortness of Breath
  • Fatigue
  • Physical Activity
  • Gait and Mobility
  • Moderate-to-vigorous physical activity
  • Non-sedentary time
  • Walking bouts 
  • Walking speed
View Report
Dermatology Psoriasis
  • Itching
  • Flaking or Scaling Skin
  • Dry, Cracked Skin that may bleed
  • Stinging, Burning, and/or Pain
  • Scratch 
  • Sleep
  • Physical Activity
  • Wake after sleep onset
  • Total scratch time
  • Step count
  • Non-sedentary time
View Report
Neurology Narcolepsy
  • Excessive Daytime Sleepiness
  • Cataplexy
  • Sleep Dysfunction
  • Cognitive Effects and Automatic Behaviors
  • Physical Activity
  • Sleep
  • Vital Signs
  • Non-sedentary time 
  • Wake after sleep onset
  • Daytime immobility bouts
View Report
Respirology Asthma
  • Shortness of Breath or Trouble Breathing
  • Frequent Coughing
  • Chest Tightness
  • Mood changes
  • Physical Activity
  • Sleep
  • Cough
  • Moderate-to-vigorous physical activity
  • Non-sedentary time
  • Step count
  • Wake after sleep onset
  • Cough
View Report
Rheumatology Osteoarthritis (OA)
  • Pain and Tenderness
  • Stiffness
  • Functional Limitations and Impaired Mobility
  • Fatigue and Sleep Disturbances
  • Physical Activity
  • Sleep
  • Gait and Mobility
  • Moderate-to-vigorous physical activity
  • Non-sedentary time
  • Step count
  • Walking bouts
  • Walking speed
  • Wake after sleep onset
View Report
Oncology Cancer Cachexia
  • Muscle Weakness
  • Fatigue/Feelings of Tiredness
  • Loss of Appetite
  • Severe Weight Loss
  • Physical Activity
  • Gait and Mobility
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Walking bouts 
  • Walking speed
View Report
Neurology Myotonic Dystrophy (DM)
  • Muscle Weakness and Myotonia
  • Fatigue
  • Pain
  • Heart Problems
  • Physical Activity
  • Gait and Mobility
  • Sleep
  • Vital Signs
  • Non-Sedentary Time
  • Step Count
  • Walking Bouts
  • Walking Speed / Cadence
  • Wrist 6 Minute Peak Activity
  • Specific Wrist Movement Metrics
  • Wake After Sleep Onset
  • Arrhythmia Burden
View Report
Neurology Spinal Muscular Atrophy (SMA)
  • Fatigue
  • Muscle Weakness and Loss of Mobility
  • Breathing Difficulties
  • Physical Activity
  • Gait and Mobility
  • Non-Sedentary Time
  • Step Count
  • Walking Bouts 
  • Walking Speed
  • Wrist 6 Minute Peak Activity 
  • Specific Wrist Movement Metrics
View Report
Neurology Kennedy’s Disease (KD) / Spinal and bulbar muscular atrophy (SBMA)
  • Muscle Weakness and Cramping
  • Fatigue
  • Breathing Difficulties
  • Balance Issues
  • Physical Activity
  • Gait and Mobility 
  • Non-Sedentary Time
  • Walking Bouts 
  • Walking Speed / Cadence
View Report
Neurology Amyotrophic Lateral Sclerosis (ALS)
  • Muscle Weakness and Fatigue
  • Shortness of Breath
  • Difficulty Sleeping
  • Speech Problems
  • Physical Activity
  • Gait and Mobility 
  • Sleep 
  • Speech
  • 6 Minute Peak Activity
  • Walking Bouts 
  • Walking Speed / Cadence
  • Step Counts
  • Specific Wrist Movement Metrics
View Report
Neurology Huntington's Disease
  • Cognitive Impairment
  • Chorea and other Motor Symptoms
  • Depression or Anxiety
  • Physical Activity
  • Gait and Mobility
  • Chorea
  • Sleep
  • Total Activity Counts
  • Walking Bouts
  • Walking Speed / Cadence
  • Step Counts
  • Wrist Activity Counts
  • Dyskinesia Score
View Report
Neurology Sarcopenia
  • Muscle Loss, Muscle Weakness, Frailty
  • Balance Problems and Falling
  • Fatigue
  • Muscle Pain
  • Physical Activity
  • Gait and Mobility
  • Sleep 
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Walking bouts 
  • Walking speed
View Report
Rheumatology Systemic Sclerosis
  • Painful cold sensitivity
  • Gastrointestinal symptoms
  • Chronic Fatigue
  • Contractures and Calcinosis of Digits
  • Physical Activity
  • Sleep 
  • Non-sedentary time 
  • Wake after sleep onset
View Report
Rheumatology Inclusion Body Myositis (IBM)
  • Muscle Weakness and Atrophy
  • Dysphagia
  • Fatigue
  • Physical Activity
  • Sleep
  • Gait and Mobility
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Step count
  • Walking speed
  • Wake after sleep onset
View Report
hematology Hemophilia
  • Joint Damage and Pain
  • Bleeding
  • Physical Activity
  • Gait and Mobility
  • Moderate-to-Vigorous Physical Activity (MVPA)
  • Non-Sedentary Time
  • Step Count
  • Walking Bouts
  • Walking Speed
View Report
Metabolic and Endocrinology Nonalcoholic Steatohepatitis (NASH)
  • Fatigue / Low Energy
  • Abdominal Pain
  • Physical Activity
  • Gait and Mobility
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Walking bouts 

Coming Soon

Oncology Lung Cancer
  • Fatigue
  • Breathing Difficulties and Shortness of Breath
  • Chronic Pain
  • Persistent Cough
  • Physical Activity
  • Sleep
  • Cough
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Step Count
  • Wake After Sleep Onset
  • Cough Frequency
View Report
Oncology Breast Cancer
  • Fatigue and weakness
  • Pain
  • Depression or Anxiety
  • Physical Activity
  • Sleep
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Step Count
  • Wake After Sleep Onset
View Report
Oncology Low-Grade Serous Ovarian Cancer
  • Fatigue
  • Bone / Pelvic Pain
  • Depression or Anxiety
  • Physical Activity
  • Gait and Mobility
  • Sleep
  • Moderate-to-Vigorous Physical Activity
  • Non-Sedentary Time
  • Step Count
  • Walking Bouts
  • Wake After Sleep Onset
View Report
Oncology Xerostomia
  • Eating Challenges
  • Fatigue and Sleep Disruption
  • Sleep
  • Cough
  • Total Sleep Time
  • Wake After Sleep Onset
  • Cough Frequency
View Report
Oncology Reducing Cardiac Late Effects in Pediatric Cancer Survivors
  • Shortness of Breath
  • Exercise Intolerance
  • Fatigue
  • Physical Activity
  • Gait and Mobility
  • Vital Signs
  • Moderate-to-Vigorous Physical Activity (MVPA)
  • Non-Sedentary Time
  • Step Count
  • Walking Bouts
  • Arrhythmia Burden
View Report
Respirology Cystic Fibrosis
  • Pulmonary Exacerbations/Infections
  • Excessive Cough
  • Gastrointestinal Symptoms
  • Fatigue
  • Physical Activity
  • Sleep
  • Cough
  • Moderate-to-Vigorous Physical Activity (MVPA)
  • Non-Sedentary Time
  • Wake After Sleep Onset
  • Cough Frequency
View Report
Respirology Non-Tuberculous Mycobacterial (NTM) Lung Infection
  • Coughing
  • Fatigue
  • Shortness of Breath
  • Physical Activity
  • Sleep
  • Cough
  • Moderate-to-Vigorous Physical Activity (MVPA)
  • Non-Sedentary Time
  • Wake After Sleep Onset
  • Cough Frequency
View Report
Dermatology Primary Biliary Cholangitis
  • Fatigue
  • Musculoskeletal Pain
  • Itchy Skin (Pruritus)
  • Physical Activity
  • Sleep
  • Nocturnal Scratch
  • Moderate-to-Vigorous Physical Activity (MVPA)
  • Non-Sedentary Time
  • Total Sleep Time
  • Wake After Sleep Onset
  • Total Scratching Time
  • Scratch Counts / Frequency
View Report
Dermatology Primary Sclerosing Cholangitis
  • Fatigue
  • Itching (Pruritus)
  • Pain
  • Physical Activity
  • Sleep
  • Nocturnal Scratch
  • Moderate-to-Vigorous Physical Activity (MVPA)
  • Non-Sedentary Time
  • Total Sleep Time
  • Wake After Sleep Onset
  • Total Scratching Time
  • Scratch Counts / Frequency
View Report

White Papers and eBooks

Explore how ActiGraph's Digital Health Technologies are reshaping healthcare. Discover the valuable insights of ActiGraph's subject matter experts through our collection of White Papers and eBooks, and revolutionize the ability to remotely obtain and analyze real-world data.

White Paper

Here, we’ve collected 4 real-world examples of clinical trials that incorporated DHTs. We assess the aspect of clinic...

White Paper

Sensor-based digital health technologies (DHTs) have revolutionized the ability to remotely obtain and analyze clinic...

White Paper

In December 2021, the FDA released its first guidance specific to the use of digital health technologies (DHTs).


Recent On-Demand Webinars

Watch previously recorded webinar discussions with industry leaders, who share their expertise in digital health technologies.

November 1, 2023

Watch this exclusive webinar as we unveil the ActiGraph LEAP™, our latest innovation in wearable digital health techn...

August 29, 2023

This 1-hour webinar explores how sensor-based digital health technologies (DHTs) can be used to collect clinically me...

April 1, 2023

More than 90% of rare diseases do not have any treatment, representing a substantial unmet need for patients.

Recent Webinars
Watch previously recorded webinar discussions with industry leaders, who share their expertise in digital health technologies.
LEAP into the Future of Patient-Centered Research: Introducing the Latest Innovation in Wearable Technology
Advancing Heart Failure Research with Digital Measures
Accelerating Rare Disease Drug Development with Wearable Digital Health Technologies

ActiGraph News

Checkout the latest press releases, updates and videos.

PENSACOLA, FL, May 15, 2025 - ActiGraph, a leading provider of wearable technology and scientific services for clinical ...
PENSACOLA, FL, April 9, 2025 -ActiGraph, a leading provider of wearable technology and scientific services for clinical ...
PENSACOLA, FL, January 7, 2025 -ActiGraph, the global leader in wearable digital health technology for clinical research...

ActiGraph Blog

Check out the latest industry focused articles.

Sensor-based DHTs offer a new opportunity to collect data for novel outcome measures in public health research in an obj...
One of the most significant challenges in managing atopic dermatitis (AD) is the lack of objective measures to evaluate ...
ActiGraph, the leading provider of wearable digital health solutions, is excited to share that we have been selected by ...

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