Digital Endpoints Resource Series



Enhancing Rheumatology Research with Wearable DHTs

Establishing clinical benefit is one of the most challenging and costly steps in developing a new therapy for patients with rheumatology conditions such as arthritis and myositis. Symptoms of rheumatology conditions can affect patients in many ways, including their physical functioning, mobility, and sleep.

With the advent of sensor-based digital health technologies (DHTs), we now have an unprecedented opportunity to remotely and continuously assess how study participants in rheumatology research function in their daily lives.

This digital endpoints guide provides information on wearable DHT adherence in rheumatology clinical trials, a list of digital endpoints available for rheumatology trials, and opportunities to advance rheumatology research with wearable DHTs, including:

  • Supporting patient-centric rheumatology condition drug development with easy-to-use wrist-worn technology
  • Collecting previously inaccessible clinical insights for rheumatology trials through novel digital endpoints
  • Passively examining physical activity, gait and mobility, movement patterns, sleep behavior, and vital signs in the patient’s natural environment

Advancing Rheumatology Research with Digital Measures

Impaired sleep is an important indicator of disease severity and treatment effect in conditions like rheumatoid arthritis. Read more about digital measures of sleep in rheumatoid arthritis clinical trial in this white paper:

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Pioneering the Digital Transformation of Clinical Research