Digital Endpoints Resource Series

Heart Failure Indication Guide

Heart Failure

Enhancing Heart Failure Research with Wearable DHTs

Establishing clinical benefit is one of the most challenging and costly steps in developing new treatments for patients with heart failure. Symptoms of heart failure can affect patients in many ways, including their physical activity, sleep, gait, and mobility.

With the advent of sensor-based digital health technologies (DHTs), we now have an unprecedented opportunity to remotely and continuously assess how study participants in heart failure research function in their daily lives.

This digital endpoints guide provides information on wearable DHT adherence in heart failure clinical trials, a list of digital endpoints available for heart failure trials, and opportunities to advance heart failure research with wearable DHTs, including

  • Supporting patient-centric cardiology drug development with easy-to-use wrist-worn technology
  • Collecting previously inaccessible clinical insights for heart failure trials through novel digital endpoints
  • Passively examining physical activity, mobility, sleep behavior, and vital signs in the patient’s natural environment

Advancing Validation of Digital Measures in Heart Failure

Learn more about how ActiGraph is collaborating with leaders in the field of heart failure research and clinical development to validate the analytical and clinical aspects of an accelerometer-based clinical outcome assessment (COA) for measuring physical activity in adults with heart failure:

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Pioneering the Digital Transformation of Clinical Research