Research Database

15 results for "Respiratory disease"

Protocol for a feasibility trial to inform the development of a breathlessness rehabilitation programme for chronic obstructive pulmonary disease and chronic heart failure (the COHERE trial)

  • Published on July 16, 2019

Introduction Adults with chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) commonly suffer from exertional dyspnoea and fatigue. Exercise training is recommended in the management of both diseases, yet many of the outcome measures traditionally reported are disease specific and may not fully acknowledge the multimorbid older adult. ...


Extrapulmonary associations of health status in severe asthma and bronchiectasis: Comorbidities and functional outcomes

  • Published on June 13, 2019

Background Severe asthma and bronchiectasis are heterogeneous diseases that contribute to disability beyond the pulmonary system. The magnitude of the impact that these extrapulmonary features has on health-related quality of life (HRQoL) is unknown. Methods We analysed the cross-sectional relationships between HRQoL (St. George's Respiratory Questionnaire; SGRQ) and extrapulmonary characteristics, ...


Clinician-Facilitated Physical Activity Intervention Versus Pulmonary Rehabilitation for Improving Physical Activity in COPD: A Feasibility Study

  • Published on Sept. 5, 2018

Abstract: Pulmonary rehabilitation (PR) may not suit all individuals with chronic obstructive pulmonary disease (COPD) and may not result in increased physical activity. Higher levels of physical activity are associated with reduced mortality and morbidity. The aim of this study was to assess the feasibility of conducting a trial to ...


Real-world Use of Rescue Inhaler Sensors, Electronic Symptom Questionnaires and Physical Activity Monitors in COPD

  • Published on February 18, 2019

Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterised by airflow obstruction and other morbidities such as respiratory symptoms, reduced physical activity and frequent bronchodilator use. Recent advances in personal digital monitoring devices can permit continuous collection of these data in COPD patients, but the relationships among them ...



The effects of exercise training in a weight loss lifestyle intervention on asthma control, quality of life and psychosocial symptoms in adult obese asthmatics: protocol of a randomized controlled trial

  • Published on Oct. 21, 2015

Background: Asthma and obesity are public health problems with increasing prevalence worldwide. Clinical and epidemiologic studies have demonstrated that obese asthmatics have worse clinical control and health related quality of life (HRQL) despite an optimized medical treatment. Bariatric surgery is successful to weight-loss and improves asthma control; however, the benefits ...


Sedentary behaviour and physical activity in bronchiectasis: a cross-sectional study

  • Published on May 13, 2015

Background The impact of bronchiectasis on sedentary behaviour and physical activity is unknown. It is important to explore this to identify the need for physical activity interventions and how to tailor interventions to this patient population. We aimed to explore the patterns and correlates of sedentary behaviour and physical activity ...


Physical Activity as a Predictor of Thirty-Day Hospital Re-Admission after a Discharge for a Clinical Exacerbation of COPD

  • Published on Aug. 28, 2014

Rationale: Physical inactivity in COPD predicts health care utilization and mortality. Objectives: To prospectively evaluate the relationship of this variable to the frequency of 30-day readmissions. Methods: Following a hospitalization for an exacerbation, consented patients discharged following an exacerbation of COPD were asked to wear an ActiGraph GT3X+ accelerometer ...


Association Between Physical Activity and Inflammatory Markers Among U.S. Adults with Chronic Obstructive Pulmonary Disease

  • Published on Dec. 20, 2013

Purpose: Chronic obstructive pulmonary disease (COPD) may cause not only inflammation in the lungs but also systemic effects. One potential strategy to reduce systemic inflammation and attenuate disease progression is physical activity (PA). However, no nationally representative studies, to our knowledge, have examined the association between objectively measured physical activity ...


Validity of physical activity monitors during daily life in patients with COPD

  • Published on Nov. 1, 2013

Background: Symptoms during physical activity and physical inactivity are hallmarks of chronic obstructive pulmonary disease (COPD). Our aim was to evaluate the validity and usability of six activity monitors in patients with COPD against the doubly labelled water (DLW) indirect calorimetry method. Methods: 80 COPD patients (mean±SD age 68±6 years and ...