Research Database

1685 results for "Research Database"

The redox-dependent regulation of satellite cells following aseptic muscle trauma (SpEED): study protocol for a randomized controlled trial

  • Published on July 31, 2019

Background Muscle satellite cells (SCs) are crucial for muscle regeneration following muscle trauma. Acute skeletal muscle damage results in inflammation and the production of reactive oxygen species (ROS) which may be implicated in SCs activation. Protection of these cells from oxidative damage is essential to ensure sufficient muscle regeneration. The ...


Neuromuscular function of the plantar flexors and predictors of peak power in middle-aged and older males

  • Published on July 30, 2019

Abstract Little evidence exists regarding the contribution of torque and velocity to the age-related decrease in peak power (PP) for the plantar flexors (PFs). A comprehensive assessment of PF neuromuscular function is necessary to elucidate age-related changes, especially between middle-aged and older adults, in order to identify early, age-related decrements. ...


Associations of School Day Sedentary Behavior and Physical Activity With Gross Motor Skills: Use of Compositional Data Analysis

  • Published on July 31, 2019

Background To examine the relationships among school day sedentary times (SED), light physical activity (LPA), and moderate to vigorous physical activity (MVPA) with gross motor skills in children using Compositional Data Analysis. Methods Participants were 409 children (mean age = 8.4 [1.8] y) recruited across 5 low-income schools. Gross motor skills were assessed using the ...


Physical Activity Levels in Peripheral Artery Disease Patients

  • Published on July 29, 2019

Background Increases in daily physical activity levels is recommended for patients with peripheral artery disease (PAD). However, despite this recommendation, little is known about the physical activity patterns of PAD patients. Objective To describe the physical activity patterns of patients with symptomatic peripheral artery (PAD) disease. Methods This cross-sectional study ...


Total energy expenditure assessed by doubly labeled water technique and estimates of physical activity in Mauritian children: analysis by gender and ethnicity

  • Published on July 29, 2019

Background/objectives In the tropical island of Mauritius, the rise in obesity has accelerated in the past decades, and could be contributed by low physical activity and increased sedentary behavior. The study objectives were to generate the first dataset of total energy expenditure (TEE), to estimate physical activity in Mauritian ...


A randomised controlled trial to investigate the use of high-frequency airway oscillations as training to improve dyspnoea in COPD

  • Published on July 29, 2019

Introduction Chronic obstructive pulmonary disease (COPD) is characterised by expiratory flow limitation resulting in symptomatic dyspnoea, sputum retention and ventilation heterogeneity. Changes in breathing mechanics affect the ability of respiratory muscles to respond to the ventilatory demands, increasing the sensation of dyspnoea. A high-frequency airway oscillating device has been developed ...


Study protocol and rationale of the “Cogni-action project” a cross-sectional and randomized controlled trial about physical activity, brain health, cognition, and educational achievement in schoolchildren

  • Published on July 26, 2019

Background Education and health are crucial topics for public policies as both largely determine the future wellbeing of the society. Currently, several studies recognize that physical activity (PA) benefits brain health in children. However, most of these studies have not been carried out in developing countries or lack the transference ...


Predicting Early Emergence of Childhood Obesity in Underserved Preschoolers

  • Published on July 26, 2019

Objective To determine the magnitude of risk of factors that contribute to the emergence of childhood obesity among low-income minority children. Study design We conducted a prospective cohort analysis of parent−child pairs with children aged 3-5 years who were nonobese (n = 605 pairs) who participated in a 3-year randomized controlled ...



Clinical benefit of two-times-per-day aclidinium bromide compared with once-a-day tiotropium bromide hydrate in COPD: a multicentre, open-label, randomised study

  • Published on July 26, 2019

Objective Chronic obstructive pulmonary disease (COPD) is mainly treated pharmaceutically with bronchodilators. The purpose of this study was to evaluate the clinical benefits of two-times-per-day aclidinium bromide (Acli-BID) compared with once-a-day tiotropium bromide hydrate (Tio-QD) in patients with COPD. Design This study was a multicentre, open-label, randomised study. Setting Fourcentres ...