Chronic obstructive pulmonary disease (COPD) is mainly treated pharmaceutically with bronchodilators. The purpose of this study was to evaluate the clinical benefits of two-times-per-day aclidinium bromide (Acli-BID) compared with once-a-day tiotropium bromide hydrate (Tio-QD) in patients with COPD.
This study was a multicentre, open-label, randomised study.
The fat mass and obesity-associated gene (FTO) rs9939609 A-allele has been associated with obesity risk. Although the exact mechanisms involved remain unknown, the FTO rs9939609 A-allele has been associated with an impaired postprandial suppression of appetite.
To explore the influence of FTO rs9939609 genotype on fasting and postprandial ...
The purpose of this study was to determine physical activity (PA) preferences associated with increases in moderate-to-vigorous physical activity (MVPA) and decrease in sedentary time in Mexican American (MA) women participating in a Promotora (community health worker)-led intervention on the U.S.-Mexico border.
Enlace (‘to link’ ...
The purpose of this study was to investigate the patterns of objectively measured sedentary behaviour in adults with intellectual disabilities.
Baseline accelerometer data were pooled from two randomized controlled trials of lifestyle behaviour change programmes for adults with intellectual disabilities. Patterns of sedentary behaviours were computed including total ...
Rapid change in the commercial market can threaten consistency of activity data comparisons as devices are superseded. Purpose: To determine the level of agreement between two generations of Fitbit™ device for step count and activity level in a free-living environment.
Thirty-seven healthy participants (17 women, 20 men; M ± SD: age 34 ± 8 ...
Overall time spent in moderate-to-vigorous intensity physical activity (MVPA) and sedentary behavior are both correlated in couples. Knowledge about the nature and psychosocial correlates of such dyadic covariation could inform important avenues for physical activity promotion.
The present study investigates hour-by-hour covariation between partners (i.e., synchrony) in ...
Objectives: To examine the differences in serum leptin levels and other relevant factors between male
methamphetamine (METH) abusers during early abstinence and healthy controls. Methods: Fifty-five male METH
abusers less than 2 weeks after quitting and 50 male healthy controls were enrolled. Abstinence was confirmed
by daily negative urine drug screening ...
Background and aims
There is high level evidence for physical activity (PA) improving outcomes in persistent pain disorders and one of the mechanisms proposed is the effect of exercise on central nociceptive modulation. Although laboratory studies and small field intervention studies suggest associations between physical activity and pain sensitivity, the ...
Acoustic and electrical brain stimulations are techniques well known to enhance memory consolidation by driving slow oscillations (SO, < 1Hz) and sleep spindle activity. Recent studies have suggested that the temporal relationship between SO and sleep spindle activity may be an important key to understanding memory consolidation mechanisms. We ...
Increasing exercise reinforcement, or decreasing sedentary reinforcement, may reduce sedentary activity and promote habitual exercise. Repeated exposures to a reinforcer may increase its reinforcing value (i.e., incentive sensitization). It is not yet known whether incentive sensitization occurs for exercise or factors associated with incentive sensitization for exercise reinforcement. ...